Penerapan Algoritma Decision Tree Dengan Optimasi Parameter Dalam Memprediksi Reaksi Autoimun Akibat Obat
DOI:
https://doi.org/10.31294/icej.v5i2.9157Keywords:
algoritma decision tree, optimasi parameter, autoimunAbstract
In the latest developments in medical technology, machine learning, especially the application of the Decision Tree algorithm, is becoming an increasingly popular approach for large-scale health data analysis. Decision Tree is known for its ability to identify hidden patterns in clinical data with interpretation that is easy for medical professionals to understand. Through the process of parameter optimization, the accuracy of the model can be significantly improved, allowing for more precise predictions of possible autoimmune reactions due to the use of certain drugs. The use of Decision Tree-based predictive models with optimized parameters not only strengthens clinical decision-making, but also paves the way for more personalized and precise treatment practices. Parameter optimization is used for the execution of all parameter variations that are set through its subprocesses. The final result recorded an optimal predictive performance of 77.50% with 98.28% more precision for the "true=0" class compared to the "true=1" class.
References
Berrar, D. (2025). Cross-Validation. In S. Ranganathan, M. Cannataro, & A. M. Khan (Eds.), Encyclopedia of Bioinformatics and Computational Biology (Second Edition) (Second Edition, pp. 638–644). Elsevier. https://doi.org/https://doi.org/10.1016/B978-0-323-95502-7.00032-4
Chen, J., & Martel, A. (2023). Cross-Validation Is All You Need: A Statistical Approach To Label Noise Estimation. https://doi.org/10.48550/arXiv.2306.13990
Fauzi, I., Nurmakarim, H., Pasha, R., & Rozikin, C. (2025). Comparative Study Of Spam Email Classfication Decision Tree Between Using Cart And J48. JATI (Jurnal Mahasiswa Teknik Informatika), 9, 4032–4036. https://doi.org/10.36040/jati.v9i3.13533
Fortes, A., Ferreira, L., Monteiro, J., Cunha, A., & Dias, C. (2024). Microbiota Transplantation And Its Role In Autoimunne Diseases: Literature Review. Revista Contemporânea, 4, e3272. https://doi.org/10.56083/RCV4N2-042
Huang, L., Liu, P., & Huang, X. (2025). InterDIA: Interpretable prediction of drug-induced autoimmunity through ensemble machine learning approaches. Toxicology, 511, 154064. https://doi.org/https://doi.org/10.1016/j.tox.2025.154064
Ming, Z. (2025). Pathogen-Induced Autoimmune Imprinting: Immune-Repertoire Alteration Syndrome. Journal of Mosaic of Autoimmunity, 1(1), 6. https://doi.org/10.53941/jmai.2025.100006
Nafi’ah, L., & Fatah, Z. (2024). Implementasi Algoritma Decision Tree Untuk Pendeteksian Penyakit Jantung. JUSIFOR : Jurnal Sistem Informasi Dan Informatika, 3, 160–165. https://doi.org/10.70609/jusifor.v3i2.5729
P, M. (2025). “A Dual Approach: Naïve Bayes and Decision Tree for Malnutrition Prediction .” International Journal Of Scientific Research In Engineering And Management, 09, 1–9. https://doi.org/10.55041/IJSREM48471
Thong, B., Vervloet, D., & Torres Jaen, M. J. (2021). Drug Allergies. https://www.worldallergy.org/component/content/article/drug-allergies-thong-b-vervloet-d-torres-jaen-mj-updated-2021?catid=16&Itemid=101
Xiaojie Huang. (2025, May 1). Drug induced Autoimmunity Prediction. https://archive.ics.uci.edu/dataset/1104/drug_induced_autoimmunity_prediction
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